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The Power of Bioprinting Webinar

Dear UKSB members,

RegenHU (Switzerland) in collaboration with Dr. Marco Domingos (The University of Manchester) and the Henry Royce Institute (The University of Manchester)will be holding a live webinar next Tuesday 30th of  June 2020, 11am-12pm (GMT) on https://app.livestorm.co/regenhu/the-power-of-bioprinting

The Power of Bioprinting 

If you want to know how 3D Bioprinting is revolutionizing the fields of Tissue Engineering and Regenerative Medicine, and how these technologies can be exploited to serve the purposes of your own research, please join us for this exciting event. We will be covering different topics including:

  • 3D Printing Scaffolds
  • Additive Manufacturing Techniques
  • What is Bioprinting
  • Introduction to Bioprinting Materials
  • 3D Bioprinting Application Examples

There will be a Q&A session at the end where you can join the discussion and interact directly with the speakers.

For more information please check out our social media posts:

Please note that this webinar is being recorded and the recording will be made available after the meeting, so please ensure you are muted when you join.

Best wishes,

Marco Domingos, PhD, CEng, FHEA, FIMechE

World Biomaterials Congress Goes Virtual in 2020

Dear WBC Community

In light of the COVID-19 global pandemic, the WBC 2020 Organising Committee has decided to cancel the physical 2020 congress. However, we are thrilled to announce that WBC 2020 will now be a fully virtual congress taking place from 11-15 December 2020 – same dates, new place, all online.

We want to thank you for your continued support for WBC 2020 and we are fully committed to creating an excellent virtual congress – an online space to meet, network, and exchange knowledge in a safe and accessible manner. Please cancel any remaining bookings you may still have for travel to Glasgow.

The WBC 2020 Virtual Congress will include live streaming and pre-recorded talks, plenary lectures, workshops, e-poster sessions, industry symposia, and more. Programme and registration information will be released soon and we are delighted to announce that the registration rates will be substantially discounted in comparison to the physical event – yet with access to even more content than before. There will be no need to decide which parallel sessions you should attend, you can go to all of them! Activities as part of the programme will start in July, building to December for Biomaterials Week.

Along with the virtual congress, we will also launch the World Biomaterials Community. Each one of you will automatically become members of the community when registering for the congress. Detailed information regarding the benefits will be released soon.

We look forward to meeting you all online – be sure to visit the WBC website for more information.

Virtual Conference

As we are currently held up by COVID-19 we have an opportunity to co-host an online virtual event with the UKs leading Centres of Doctoroal Training focussed on Regenerative medicine.

24-25th June 2020

This will be a free conference for UKSB members and those involved in the CDTs. We hope that many will join from near and far to highlight our research and support the development of further network developments.

Prof Liam Grover, University of Birmingham, will be giving a keynote presentation, with more details to follow shortly.

There will be a range of sessions held across our focussed research areas, with talk slots and online poster presentations. If you wish to join our virtual audience and/or submit a poster please register for membership and get in touch.

PhD Opportunity:

Nano Silver-Hydroxyapatite Coatings – biocompatibility with oral cells to improve abutment integrity for periodontal health.

Please click here for information regarding a PhD position that is available at The University of Plymouth. 

Project description

This project is an exciting opportunity to develop novel silver-hydroxyapatite nanocoatings to reduce failure of dental implants. The interdisciplinary project combines nanotechnology with leading biomedical science expertise, in a real-world clinical setting to investigate the biocompatibility of antibacterial nanocoatings with oral cells to improve abutment integrity for periodontal health. 

Despite the high success rates of dental implants, 5-10% of them are still reported to fail and must be removed. One of the most common causes of implant failure is peri-implantitis, which is caused by bacterial biofilm formation on the implant surfaces. Modification of the surface nanotopography has been identified as one of the strategies to control bacterial adherence to implants and improve clinical outcomes. 

Silver nanoparticles are known for their antibacterial properties, whereas hydroxyapatite is a chemical similar to the mineral component of natural bone and teeth. Our team has demonstrated that silver-hydroxyapatite hybrid nanocoatings applied to the surface of medical implants are antibacterial but also biocompatible with human osteoblasts, suggesting good fusion of the implants to the jaw bone is achieved. However, shrinkage of the gingiva at the abutment margins, with subsequent infection and micro-leakage in the sub-gingival crevice can lead to implant failure, as well as other oral health problems. 

We are seeking a highly motivated individual to work in a rich academic environment within a world-leading research group on nanosafety and biomaterials. The successful candidate will receive excellent training provided at the School of Engineering, Computing and Mathematics, School of Biomedical Sciences and Peninsula Schools of Medicine and Dentistry.

For further information please contact:

Dr Alexander Besinis 

TERMIS-EU Update

The TERMIS-EU Chapter hosted in Manchester UK has been postponed to March 2023

Due to the challenging issues current facing us with Covid-19, the organisers of TERMIS_EU 2020 have decided to postpone the event which was due to be held this May in Manchester.

Due to the escalating situation with COVID-19 (Coronavirus) around the world and the global restrictions regarding travel and event organisation, the Organizing Committee of the TERMIS-EU 2020 Chapter Meeting has decided to postpone the Meeting. There has been considerable debate on the best way forward, with discussions around rescheduling this year or going virtual. As no suitable dates could be identified in 2020 with uncertainty surrounding us, and with plans already in place for the meetings in 2021 (World Congress in Maastricht, The Netherlands) and 2022 (EU Meeting in Krakow, Poland) the Manchester meeting of TERMIS-EU will now be held 27th and 30th March 2023.

Further details about existing registrations and the arrangements for 2023 will be announced shortly. 

UKSB were scheduled to host a joint symposium within the conference with the Royal Society of Chemistry Biomaterials Chemistry group. We hope that we will have this opportunity, and look forward to supporting the conference in 2023.

WBC2020 – further update and exciting news!

During these challenging times the WBC Executive Committee has been involved in many discussions with the IUSBSE representatives acting as advocates for the various regional Biomaterials societies and have decided to reschedule the Congress to 11th-16th of Dec 2020. This was a difficult decision, as I’m sure many are aware, with many options open and no one right answer. Many other conferences are being cancelled altogether, some are investigating the potential to go virtual; the WBC is a major event and we are very lucky to have such a prestigious event planned within the UK.

If attendees have any specific queries regarding the conference registration and the policy relating to Modification & Cancellation – this can be found here. For those who may not be able to attend the organisers are also in the process of extending the deadline for cancellation beyond the 15th of April 2020 and hope to announce this new date shortly. But before you may think about cancelling, please do look out for the exciting and creative opportunities that will be showcased over the coming months with the introduction of a WBC2020 Virtual Community and Meetings Platform.

The WBC2020 Executive Committee has also been working with PCO (MCI) in light of the COVID-19 crisis. Specifically, in addition to normal day-to-day activities, they have been working on developing a mitigation strategy in the case that there are further restrictions due to the pandemic later in the year. This strategy is based on the development of digital engagement and virtual meetings solutions.

It was exciting to hear that not only have they planned for potential difficulties, they are also launching WBC Online, a comprehensive digital space where all WBC registrants and international biomaterials specialists can come together in online discussion forum to share, learn and engage with each other. The WBC Online community will be able to join online special interest groups and gain access to a valued pool of e-resources in the run up to, during WBC Live and beyond. In addition to hot news, product development and up and coming biomaterial society events featured on the platform, all WBC registrants will be able to view and participate in a schedule of online WBC interactive webinars, society symposia, WBC sponsored satellite webinars and international guest lectures to be broadcast in the months running up to WBC Live. All WBC registrants will be auto-enrolled into WBC Online and will benefit from all of its features, including live streamed sessions broadcast live from WBC Live. Additionally, all registrants will enjoy access to WBC Online for a period of two years as part of their 2020 registration fees.

Some attendees and group PIs have expressed concerns over the rescheduling of the event for PhDs or PDRAs who may no longer be in their employ in Dec. The WBC Executive Committee are in the process of discussing solutions to this and will be in a position to update over the coming weeks.

The UKSB will still be hosting a special workshop as part of the event, and look forward to many of you attending. We are excited about the prospect of engaging widely during the physical event in Glasgow, and certainly the opportunities that a virtual platform may enable.

In the run up to this event the UKSB will also be co-hosting a free virtual event with many of the UK Centres of Doctoral Training (CDT) engaged in biomaterials and regenerative medicine research. Updates for this will be coming soon, but there will be an opportunity to take part with a call for abstracts coming out soon.

The UKSB council take this opportunity to wish you and your families well. Please keep safe and look after each other, even if virtually.

World Biomaterials Congress

COVID-19 (Coronavirus) Statement

Following the recent developments in the COVID-19 (coronavirus) situation, we have taken the difficult decision to postpone the 11th World Biomaterials Congress which was due to take place in Glasgow on 19 – 24 May 2020.

The UKSB will be holding a special meeting within the World Congress and are proud to be a part of, and support the international conference.

As demands on the health service will increase significantly over the next few months, and the UK government has recently recommended social distancing and restricting travel we do not feel it is appropriate for us to run large-scale events. Our congress brings together professionals from all around the world, and our Board of Trustees is keen to avoid the risk of transmission to our delegates. 

The congress will now take place from 11 – 16 December 2020 remaining at the SEC in Glasgow and we will automatically be moving the current programme over to the December schedule and hope that you are available to attend at this time.

If you are taking part in this congress we will be in touch with further details soon.

WBC Conference Secretariat

wbc2020.org/

Job Advert

Research Assistant, Faculty of Dentistry, Oral and Craniofacial Sciences

King’s College London (KCL), London, United Kingdom

The salary will be paid at Grade 5, £32,676 per annum, inclusive of £3,500 per annum London Allowance.
This post will be offered on a fixed-term contract for 12 months.
This is a full-time post.

Applications are invited for Research Assistant to work alongside with Dr Sherif Elsharkawy in the Faculty of Dentistry, Oral and Craniofacial Science at King’s College London. The research project will be focused on the design, synthesis and purification of recombinant mutated and non-mutated proteins, known to be involved in dental hard tissue development. These proteins will be employed to fabricate protein-based matrices to understand biomineralization mechanisms at multiple lengthscale. The goal will be to generate in vitro models to investigate developmental and pathological mineralisation. Alongside with the principal investigator, the candidate will play a major role in setting up a Biomineralization Lab at King’s College London.

Ideally, you will have (or near completion) a PhD in Chemistry, Materials Science, Molecular Biology, or Engineering and experience in biomineralization as well as one or more of the following areas:

1) Protein Production.

2) Protein-based mineralization.

3) Disordered proteins.

4) Hierarchical materials.

The selection process will include a panel interview and a presentation.

To apply, please register with the King’s College London application portal and complete your application online.

Informal enquiries should be emailed to  Dr Sherif Elsharkawy at sherif.elsharkawy@kcl.ac.uk

Closing date: Midnight on Friday 24 January 2020

Dr Caroline J Harrison Lab-2-Lab Award

Postdoctoral Research Associate, Bioengineering and Healthcare Technologies Group,School of Clinical Dentistry, University of Sheffield

Host laboratory:
Prof Alastair Sloan, Dr Wayne Nishio Ayre and Mr Jabur Khan The Mineralised Tissue Group, Dental School, Cardiff University

The purpose of the placement was to develop an ex vivo bone infection model to screen antimicrobial and osteogenic bone regeneration materials. The Mineralised Tissue Group at Cardiff University has considerable experience of developing these models so a 3 week placement was undertaken to in order to understand the methods involved in the development of ex vivo models.

Prof Alastair Sloan and Dr Wayne Nishio Ayre arranged that I could work with Mr Jabur Khan, a PhD student currently developing an ex vivo bone infection model. During the first week Jabur demonstrated the ex vivo bone infection model that he is currently developing and trained me in the various techniques including the sectioning of the bone and the setting up of Trowell-type cultures which are essential for keeping the bone viable whilst preventing excessive migration of the cells out of the bone. Jabur also showed me the immunohistological techniques he is currently optimising to be able to assess the distribution of biomarkers in the bone models. Furthermore, I observed the setting up of other ex vivo models including a model to assess the viability of the gingiva in a mandible culture model which Dr Amr Alraies is currently researching.

Over the next two weeks I was able to set up my own ex vivo cultures in order to investigate the effect of the dual action bone paste currently under development by the research team at The University of Sheffield. It was very useful to get hands on experience setting up the model as well as investigating different methods to apply the paste to the model. I assessed my models using viability assays and histological techniques. My lab work went very smoothly which was in part due to the fantastic technical support staff at the School of Dentistry, University of Cardiff. The laboratory managers and technicians including Dr Fiona Gagg, Dr Sarah Youde and Ms Wendy Rowe all provided excellent inductions and support material, which allowed me to work in the laboratories with ease and confidence.

I was very pleased with the consistency of the data from the assays I carried out, and I would say this was my professional highlight of the visit. My personal highlights were some lovely sunny lunches in the small nature haven provided directly outside the entrance of the University Hospital of Wales (see picture). Due to the success of this placement we are now looking forward to establishing future collaborative projects between the Mineralised Tissue Group at Cardiff University and the Bioengineering and Healthcare Technologies Group at The University of Sheffield.

Banner caption: SHY-SY5Y artistic (Jordan Roe)
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